XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
Synonyms:
CMM6
Species:
Human XRCC3 (7517), Mouse Xrcc3 (74335), Rat Xrcc3 (100359601), domestic guinea pig Xrcc3 (100723056), chicken XRCC3 (423485), Zebrafish xrcc3 (541414), Thale Cress XRCC3 (835850), cow XRCC3 (768244), dog XRCC3 (100687200), naked mole-rat Xrcc3 (101699387)
UniProtKB ID:
Gene ID:
- Human(7517) Summary: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
- Mouse(74335) X-ray repair complementing defective repair in Chinese hamster cells 3
- Rat(100359601) X-ray repair complementing defective repair in Chinese hamster cells 3
- domestic guinea pig(100723056) X-ray repair complementing defective repair in Chinese hamster cells 3
- chicken(423485) X-ray repair complementing defective repair in Chinese hamster cells 3
- Zebrafish(541414) X-ray repair complementing defective repair in Chinese hamster cells 3
- Thale Cress(835850) DNA repair protein XRCC3-like protein
- cow(768244) X-ray repair complementing defective repair in Chinese hamster cells 3
- dog(100687200) X-ray repair complementing defective repair in Chinese hamster cells 3
- naked mole-rat(101699387) X-ray repair complementing defective repair in Chinese hamster cells 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-XRCC4 antibody produced in rabbit, whole antiserum,
Species Reactivity
human
Application
western blot