UBE2E3
ubiquitin-conjugating enzyme E2E 3
Synonyms:
UBCH9, UbcM2
Species:
Human UBE2E3 (10477), Mouse Ube2e3 (22193), Rat Ube2e3 (295686), domestic guinea pig Ube2e3 (100718900), cow UBE2E3 (534349), Zebrafish ube2e3 (321689), chicken UBE2E3 (424122), domestic cat UBE2E3 (101081321), dog UBE2E3 (612823), naked mole-rat Ube2e3 (101708301) ...More
UniProtKB ID:
Gene ID:
- Human(10477) Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013]
- Mouse(22193) ubiquitin-conjugating enzyme E2E 3
- Rat(295686) ubiquitin-conjugating enzyme E2E 3
- domestic guinea pig(100718900) ubiquitin-conjugating enzyme E2E 3
- cow(534349) ubiquitin-conjugating enzyme E2E 3
- Zebrafish(321689) ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
- chicken(424122) ubiquitin-conjugating enzyme E2E 3
- domestic cat(101081321) ubiquitin-conjugating enzyme E2E 3
- dog(612823) ubiquitin-conjugating enzyme E2E 3
- naked mole-rat(101708301) ubiquitin-conjugating enzyme E2E 3
- Horse(100067766) ubiquitin-conjugating enzyme E2E 3
- sheep(101121069) ubiquitin-conjugating enzyme E2E 3
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