Skip to Content
Merck

TRIM63

tripartite motif containing 63, E3 ubiquitin protein ligase

Synonyms:
IRF, MURF1, MURF2, RNF28, SMRZ
Species:
UniProtKB ID:
Gene ID:
  • Human(84676) Summary: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]
  • Mouse(433766) tripartite motif-containing 63
  • Rat(140939) tripartite motif containing 63, E3 ubiquitin protein ligase
  • sheep(101113132) tripartite motif containing 63, E3 ubiquitin protein ligase
  • sheep(100144767) tripartite motif containing 63, E3 ubiquitin protein ligase
  • cow(528912) tripartite motif containing 63
  • domestic guinea pig(100716828) tripartite motif containing 63, E3 ubiquitin protein ligase
  • Horse(100071234) tripartite motif containing 63, E3 ubiquitin protein ligase
  • Zebrafish(415223) tripartite motif containing 63
  • chicken(426754) tripartite motif containing 63, E3 ubiquitin protein ligase
  • domestic cat(101083951) tripartite motif containing 63, E3 ubiquitin protein ligase
  • dog(487362) tripartite motif containing 63, E3 ubiquitin protein ligase
  • naked mole-rat(101705659) tripartite motif containing 63, E3 ubiquitin protein ligase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TRIM63 antibody produced in mouse, clone 6G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-MURF1/TRIM63, N-Terminal antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
ELISA
immunohistochemistry
Anti-TRIM63 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot