TRIM22
tripartite motif containing 22
GPSTAF50, RNF94, STAF50
- Human(10346) Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
- domestic cat(101082007) tripartite motif containing 22
- dog(485284) tripartite motif containing 22
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Antibodies
Anti-TRIM22 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
human
western blot