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Merck

TNFRSF21

tumor necrosis factor receptor superfamily, member 21

Synonyms:
BM-018, CD358, DR6
Species:
Human TNFRSF21 (27242), Mouse Tnfrsf21 (94185), Rat Tnfrsf21 (316256), Domestic Rabbit TNFRSF21 (100349758), Horse TNFRSF21 (100068460), dog TNFRSF21 (609964), Zebrafish tnfrsf21 (564874), chicken TNFRSF21 (422062), domestic cat TNFRSF21 (101090616), domestic guinea pig Tnfrsf21 (100731666) ...More
UniProtKB ID:
O75509, B2RDI9, Q0D2P5, Q96D86
Gene ID:
  • Human(27242) Summary: This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013]
  • Mouse(94185) tumor necrosis factor receptor superfamily, member 21
  • Rat(316256) tumor necrosis factor receptor superfamily, member 21
  • Domestic Rabbit(100349758) tumor necrosis factor receptor superfamily, member 21
  • Horse(100068460) tumor necrosis factor receptor superfamily, member 21
  • dog(609964) tumor necrosis factor receptor superfamily, member 21
  • Zebrafish(564874) tumor necrosis factor receptor superfamily, member 21
  • chicken(422062) tumor necrosis factor receptor superfamily, member 21
  • domestic cat(101090616) tumor necrosis factor receptor superfamily, member 21
  • domestic guinea pig(100731666) tumor necrosis factor receptor superfamily, member 21
  • naked mole-rat(101713683) tumor necrosis factor receptor superfamily, member 21
  • cow(537922) tumor necrosis factor receptor superfamily, member 21
  • sheep(101117284) tumor necrosis factor receptor superfamily, member 21

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB3500255
Anti-DR6 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB2102490
Anti-TNFRSF21 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot