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SOS1

son of sevenless homolog 1 (Drosophila)

Synonyms:
GF1, GGF1, GINGF, HGF, NS4
Species:
UniProtKB ID:
Gene ID:
  • Human(6654) Summary: This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
  • Mouse(20662) son of sevenless homolog 1 (Drosophila)
  • Rat(313845) Son of sevenless homolog 1 (Drosophila)
  • Thale Cress(814729) sodium/hydrogen exchanger 7
  • Zebrafish(556286) son of sevenless homolog 1 (Drosophila)
  • chicken(431192) son of sevenless homolog 1 (Drosophila)
  • dog(483042) son of sevenless homolog 1 (Drosophila)
  • Horse(100053889) son of sevenless homolog 1 (Drosophila)
  • domestic cat(101098862) son of sevenless homolog 1 (Drosophila)
  • cow(537682) son of sevenless homolog 1 (Drosophila)
  • sheep(101118865) son of sevenless homolog 1 (Drosophila)
  • domestic guinea pig(100721165) son of sevenless homolog 1 (Drosophila)
  • naked mole-rat(101707893) son of sevenless homolog 1 (Drosophila)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SOS1 antibody produced in mouse, clone 4C1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay