SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
Synonyms:
EAAT2, GLT-1
Species:
Human SLC1A2 (6506), Mouse Slc1a2 (20511), Rat Slc1a2 (29482), naked mole-rat Slc1a2 (101701278), domestic guinea pig Slc1a2 (100731435), chicken SLC1A2 (423156), dog SLC1A2 (403750), cow SLC1A2 (541119)
UniProtKB ID:
Gene ID:
- Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
- Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
- Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
- naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
- domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
- chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
- dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
- cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SLC1A2 antibody produced in mouse, clone 4G8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-Excitatory Amino Acid Transporter (GLT-1) Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
rat
Application
Anti-SLC1A2, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human