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Merck

SLC18A2

solute carrier family 18 (vesicular monoamine transporter), member 2

Synonyms:
SVAT, SVMT, VAT2, VMAT2
Species:
UniProtKB ID:
Gene ID:
  • Human(6571) Summary: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]
  • Mouse(214084) solute carrier family 18 (vesicular monoamine), member 2
  • Rat(25549) solute carrier family 18 (vesicular monoamine transporter), member 2
  • Horse(100058805) solute carrier family 18 (vesicular monoamine), member 2
  • cow(282471) solute carrier family 18 (vesicular monoamine), member 2
  • domestic guinea pig(100719098) solute carrier family 18 (vesicular monoamine), member 2
  • domestic cat(101086507) solute carrier family 18 (vesicular monoamine), member 2
  • dog(486908) solute carrier family 18 (vesicular monoamine), member 2
  • naked mole-rat(101725597) solute carrier family 18 (vesicular monoamine), member 2
  • chicken(423921) solute carrier family 18 (vesicular monoamine), member 2
  • sheep(101104796) solute carrier family 18 (vesicular monoamine), member 2
  • Zebrafish(553304) solute carrier family 18 (vesicular monoamine), member 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-VMAT2/SLC18A2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
immunohistochemistry

western blot
Anti-VMAT2 antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Benzphetamine hydrochloride, ,
Species
human
D-Amphetamine hemisulfate salt solution, 1.0 mg/mL in methanol, analytical standard, for drug analysis,
Species
human
Dexamfetamine sulfate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Reserpine, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
Reserpine, crystallized, ≥99.0% (HPLC),
Species
human