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Merck

SIRT5

sirtuin 5

Synonyms:
SIR2L5
Species:
UniProtKB ID:
Gene ID:
  • Human(23408) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010]
  • Mouse(68346) sirtuin 5
  • Rat(306840) sirtuin 5
  • Goat(100860989) sirtuin 5
  • cow(507347) sirtuin 5
  • naked mole-rat(101718891) sirtuin 5
  • dog(478726) sirtuin 5
  • domestic cat(101089862) sirtuin 5
  • chicken(420834) sirtuin 5
  • Zebrafish(436878) sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
  • domestic guinea pig(100718110) sirtuin 5
  • sheep(101104099) sirtuin 5

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SIRT5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
goat, guinea pig, human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SIRT5, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Sirtuin 5 human, recombinant, expressed in E. coli, ≥50% (SDS-PAGE),
Species
human