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Merck

SET

SET nuclear oncogene

Synonyms:
2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA
Species:
UniProtKB ID:
Gene ID:
  • Human(6418) Summary: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(56086) SET nuclear oncogene
  • Rat(307947) SET nuclear oncogene
  • fruit fly(41844) CG4299 gene product from transcript CG4299-RA
  • chicken(417210) SET nuclear oncogene
  • dog(608952) SET nuclear oncogene
  • domestic cat(101081583) SET nuclear oncogene
  • cow(538444) SET nuclear oncogene
  • sheep(101118680) SET nuclear oncogene
  • domestic guinea pig(100715138) SET nuclear oncogene
  • naked mole-rat(101720656) SET nuclear oncogene

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SET, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-SET (56-70) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-SET antibody produced in mouse, clone M1-F5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Monoclonal Anti-SET antibody produced in mouse, clone SET7, tissue culture supernatant,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-SET antibody, Mouse monoclonal, clone SET51, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
western blot

Proteins

Product Number
Description
Species
Protein Phosphatase 2A Inhibitor Protein, 1‑α human, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Species
human