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Merck

SERPINA3

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

Synonyms:
AACT, ACT, GIG25
Species:
Human SERPINA3 (12), chicken SERPINA3 (772339), cow SERPINA3 (617667), dog SERPINA3 (480425), domestic guinea pig Serpina3 (100726710), naked mole-rat Serpina3 (101719778), domestic cat SERPINA3 (101089197)
UniProtKB ID:
P01011, B3KVQ7, Q13703, Q2TU87, Q2TU88, Q59GP9, Q6LBY8, Q6LDT7
Gene ID:
  • Human(12) Summary: The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
  • chicken(772339) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • cow(617667) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • dog(480425) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • domestic guinea pig(100726710) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • naked mole-rat(101719778) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
  • domestic cat(101089197) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2108215
Anti-SERPINA3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
SAB1405413
Anti-SERPINA3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
A9285
α1-Antichymotrypsin from human plasma, ≥92.5% (SDS-PAGE), lyophilized powder,
Species
human
SRP6425
SERPIN A3 human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Species
human
P3360
Prostate Specific Antigen–α1-Antichymotrypsin Complex human, ≥99% (SDS-PAGE), buffered aqueous solution,
Species
human