SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
Synonyms:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Species:
Human SCN8A (6334), Mouse Scn8a (20273), Rat Scn8a (29710), chicken SCN8A (100857835), dog SCN8A (477604), Horse SCN8A (100052777), cow SCN8A (537277), naked mole-rat Scn8a (101711868), domestic guinea pig Scn8a (100734003), sheep SCN8A (101113744) ...More
UniProtKB ID:
Gene ID:
- Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
- Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
- chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
- dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
- Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
- cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
- naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
- domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
- sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
- domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
- chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Sodium Channel PN4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
rat
Application
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Species Reactivity
mammals
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Product Number
Description
Species
Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human