RRBP1
ribosome binding protein 1
Synonyms:
ES/130, ES130, RRp, hES
Species:
Human RRBP1 (6238), Mouse Rrbp1 (81910), Rat Rrbp1 (311483), cow RRBP1 (505941), naked mole-rat Rrbp1 (101712445), sheep RRBP1 (101121793), dog RRBP1 (403809), chicken RRBP1 (396414), Horse RRBP1 (100050674), domestic cat RRBP1 (100101124)
UniProtKB ID:
Gene ID:
- Human(6238) Summary: This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]
- Mouse(81910) ribosome binding protein 1
- Rat(311483) ribosome binding protein 1
- cow(505941) ribosome binding protein 1
- naked mole-rat(101712445) ribosome binding protein 1
- sheep(101121793) ribosome binding protein 1 homolog 180kDa (dog)
- dog(403809) ribosome binding protein 1 homolog 180kDa (dog)
- chicken(396414) ribosome binding protein 1 homolog 180kDa (dog)
- Horse(100050674) ribosome binding protein 1 homolog 180kDa (dog)
- domestic cat(100101124) ribosome binding protein 1 homolog 180kDa (dog)
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