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Merck

RHCE

Rh blood group, CcEe antigens

Synonyms:
CD240CE, RH, RH30A, RHC, RHE, RHIXB, RHPI, Rh4, RhIVb(J), RhVI, RhVIII
Species:
Human RHCE (6006), chicken RHCE (419591), domestic guinea pig Rhce (100718214), dog RHCE (612220)
UniProtKB ID:
P18577, A7DW68, B7UDF3, B7UDF4, B7UDF5, B7UDF6, B7UDF7, B7UDF8
Gene ID:
  • Human(6006) Summary: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms. [provided by RefSeq, Jul 2008]
  • chicken(419591) Rh blood group, CcEe antigens
  • domestic guinea pig(100718214) Rh blood group, CcEe antigens
  • dog(612220) Rh blood group, CcEe antigens

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