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Merck

PRDX3

peroxiredoxin 3

Synonyms:
AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III
Species:
UniProtKB ID:
Gene ID:
  • Human(10935) Summary: This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11757) peroxiredoxin 3
  • Rat(64371) peroxiredoxin 3
  • dog(477839) peroxiredoxin 3
  • domestic cat(101088618) peroxiredoxin 3
  • Zebrafish(373079) peroxiredoxin 3
  • chicken(428986) peroxiredoxin 3
  • naked mole-rat(101719189) peroxiredoxin 3
  • domestic guinea pig(100716687) peroxiredoxin 3
  • cow(281998) peroxiredoxin 3
  • sheep(101106731) peroxiredoxin 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PRDX3 antibody produced in mouse, clone 1E3-B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot
Anti-PRDX3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Peroxiredoxin 3 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
microarray
western blot
Anti-PRDX3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-AOP1 antibody, Mouse monoclonal, clone AOP-38, purified from hybridoma cell culture,
Species Reactivity
canine, chicken, hamster, human, monkey, mouse, rat
Application
ELISA
microarray

western blot