PLCD1
phospholipase C, delta 1
Synonyms:
NDNC3, PLC-III
Species:
Human PLCD1 (5333), Mouse Plcd1 (18799), Rat Plcd1 (24655), domestic guinea pig Plcd1 (100715613), chicken PLCD1 (420416), sheep PLCD1 (101110367), naked mole-rat Plcd1 (101715010), cow PLCD1 (281986), dog PLCD1 (485586), domestic cat PLCD1 (101087777) ...More
UniProtKB ID:
Gene ID:
- Human(5333) Summary: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Mouse(18799) phospholipase C, delta 1
- Rat(24655) phospholipase C, delta 1
- domestic guinea pig(100715613) phospholipase C, delta 1
- chicken(420416) phospholipase C, delta 1
- sheep(101110367) phospholipase C, delta 1
- naked mole-rat(101715010) phospholipase C, delta 1
- cow(281986) phospholipase C, delta 1
- dog(485586) phospholipase C, delta 1
- domestic cat(101087777) phospholipase C, delta 1
- Horse(100054233) phospholipase C, delta 1
- cow(790012) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1-like
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