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Merck

PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

Synonyms:
LCCS3, PIP5K-GAMMA, PIP5Kgamma, PIPKIg_v4
Species:
Human PIP5K1C (23396), Mouse Pip5k1c (18717), Rat Pip5k1c (314641), domestic guinea pig Pip5k1c (100717867), cow PIP5K1C (508819), dog PIP5K1C (485054), sheep PIP5K1C (101115537), naked mole-rat Pip5k1c (101700633), domestic cat PIP5K1C (101097791), chicken PIP5K1C (420072)
UniProtKB ID:
O60331, B7Z9E7, C6GIJ7, C6GIJ8, Q7LE07
Gene ID:
  • Human(23396) Summary: This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010]
  • Mouse(18717) phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
  • Rat(314641) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • domestic guinea pig(100717867) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • cow(508819) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • dog(485054) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • sheep(101115537) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • naked mole-rat(101700633) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • domestic cat(101097791) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
  • chicken(420072) phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

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Antibodies

Product Number
Description
Species Reactivity
Application
K1894
Anti-PIP5K1C (C-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
SRP5293
PIP5K1C, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human