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PDGFA

platelet-derived growth factor alpha polypeptide

Synonyms:
PDGF-A, PDGF1
Species:
UniProtKB ID:
Gene ID:
  • Human(5154) Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18590) platelet derived growth factor, alpha
  • Rat(25266) platelet-derived growth factor alpha polypeptide
  • domestic cat(101087287) platelet-derived growth factor alpha polypeptide
  • naked mole-rat(101725739) platelet-derived growth factor alpha polypeptide
  • chicken(374196) platelet-derived growth factor alpha polypeptide
  • dog(491597) platelet-derived growth factor alpha polypeptide
  • cow(505908) platelet-derived growth factor alpha polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PDGFA antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
Anti-Platelet-Derived Growth Factor antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
ELISA
neutralization

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Suramin sodium salt, ≥98% (TLC),
Species
human

Proteins

Product Number
Description
Species
PDGF-AA human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
human
PDGF-AA from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
Platelet-Derived Growth Factor-AB human, PDGF-AB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
Platelet-Derived Growth Factor from human platelets, PDGF, lyophilized powder, suitable for cell culture,
Species
human
Platelet-Derived Endothelial Cell Growth Factor human, recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
human