PDE11A
phosphodiesterase 11A
Synonyms:
PPNAD2
Species:
Human PDE11A (50940), Mouse Pde11a (241489), Rat Pde11a (140928), Zebrafish pde11a (561338), cow PDE11A (524446), Horse PDE11A (100053692), chicken PDE11A (424133), domestic cat PDE11A (101100071), sheep PDE11A (101103537), dog PDE11A (488422) ...More
UniProtKB ID:
Gene ID:
- Human(50940) Summary: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(241489) phosphodiesterase 11A
- Rat(140928) phosphodiesterase 11A
- Zebrafish(561338) phosphodiesterase 11a
- cow(524446) phosphodiesterase 11A
- Horse(100053692) phosphodiesterase 11A
- chicken(424133) phosphodiesterase 11A
- domestic cat(101100071) phosphodiesterase 11A
- sheep(101103537) phosphodiesterase 11A
- dog(488422) phosphodiesterase 11A
- Domestic Rabbit(100341520) phosphodiesterase 11A
- domestic guinea pig(100302674) phosphodiesterase 11A
- naked mole-rat(101700959) phosphodiesterase 11A
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