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Merck

PCBP4

poly(rC) binding protein 4

Synonyms:
CBP, LIP4, MCG10
Species:
Human PCBP4 (57060), Mouse Pcbp4 (59092), Rat Pcbp4 (363133), sheep PCBP4 (101112854), Domestic Rabbit PCBP4 (100345078), dog PCBP4 (476603), naked mole-rat Pcbp4 (101699011), cow PCBP4 (506889), domestic guinea pig Pcbp4 (100722291), domestic cat PCBP4 (101100287)
UniProtKB ID:
P57723, Q96AH7
Gene ID:
  • Human(57060) Summary: This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(59092) poly(rC) binding protein 4
  • Rat(363133) poly(rC) binding protein 4
  • sheep(101112854) poly(rC) binding protein 4
  • Domestic Rabbit(100345078) poly(rC) binding protein 4
  • dog(476603) poly(rC) binding protein 4
  • naked mole-rat(101699011) poly(rC) binding protein 4
  • cow(506889) poly(rC) binding protein 4
  • domestic guinea pig(100722291) poly(rC) binding protein 4
  • domestic cat(101100287) poly(rC) binding protein 4

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