P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
Synonyms:
Species:
Human P4HA3 (283208), Mouse P4ha3 (320452), Rat P4ha3 (361612), sheep P4HA3 (101104856), Zebrafish p4ha3 (563281), chicken P4HA3 (419057), dog P4HA3 (609381), naked mole-rat P4ha3 (101711128), domestic guinea pig P4ha3 (100735153), domestic cat P4HA3 (101081160)
UniProtKB ID:
Gene ID:
- Human(283208) Summary: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(320452) procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
- Rat(361612) prolyl 4-hydroxylase, alpha polypeptide III
- sheep(101104856) prolyl 4-hydroxylase, alpha polypeptide III
- Zebrafish(563281) prolyl 4-hydroxylase, alpha polypeptide III
- chicken(419057) prolyl 4-hydroxylase, alpha polypeptide III
- dog(609381) prolyl 4-hydroxylase, alpha polypeptide III
- naked mole-rat(101711128) prolyl 4-hydroxylase, alpha polypeptide III
- domestic guinea pig(100735153) prolyl 4-hydroxylase, alpha polypeptide III
- domestic cat(101081160) prolyl 4-hydroxylase, alpha polypeptide III
- cow(414348) prolyl 4-hydroxylase, alpha polypeptide III
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