MAPK1
mitogen-activated protein kinase 1
Synonyms:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Species:
Human MAPK1 (5594), Mouse Mapk1 (26413), Rat Mapk1 (116590), chicken MAPK1 (373953), Zebrafish mapk1 (360144), dog MAPK1 (477575), domestic cat MAPK1 (101087614), sheep MAPK1 (101115485), cow MAPK1 (327672), naked mole-rat Mapk1 (101706099)
UniProtKB ID:
Gene ID:
- Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(26413) mitogen-activated protein kinase 1
- Rat(116590) mitogen activated protein kinase 1
- chicken(373953) mitogen-activated protein kinase 1
- Zebrafish(360144) mitogen-activated protein kinase 1
- dog(477575) mitogen-activated protein kinase 1
- domestic cat(101087614) mitogen-activated protein kinase 1
- sheep(101115485) mitogen-activated protein kinase 1
- cow(327672) mitogen-activated protein kinase 1
- naked mole-rat(101706099) mitogen-activated protein kinase 1
- domestic guinea pig(100715180) mitogen-activated protein kinase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-ERK2/MAPK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
xenopus, bovine, chicken, chimpanzee, human, mouse
Application
ELISA
western blot
western blot
Anti-MAPK 1/2 Antibody, from rabbit,
Species Reactivity
bovine, canine, human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
MONOCLONAL ANTI-ERK2 antibody produced in mouse, clone 814CT5.4.2, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-phospho-p44/42 MAP Kinase (pThr202) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human