LMAN1
lectin, mannose-binding, 1
Synonyms:
ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
Species:
Human LMAN1 (3998), Mouse Lman1 (70361), Rat Lman1 (116666), Horse LMAN1 (100050262), naked mole-rat Lman1 (101723407), chicken LMAN1 (426849), domestic cat LMAN1 (101080833), Zebrafish lman1 (559775), Domestic Rabbit LMAN1 (100354112), dog LMAN1 (476186) ...More
UniProtKB ID:
Gene ID:
- Human(3998) Summary: The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq, Jul 2008]
- Mouse(70361) lectin, mannose-binding, 1
- Rat(116666) lectin, mannose-binding, 1
- Horse(100050262) lectin, mannose-binding, 1
- naked mole-rat(101723407) lectin, mannose-binding, 1
- chicken(426849) lectin, mannose-binding, 1
- domestic cat(101080833) lectin, mannose-binding, 1
- Zebrafish(559775) lectin, mannose-binding, 1
- Domestic Rabbit(100354112) lectin, mannose-binding, 1
- dog(476186) lectin, mannose-binding, 1
- domestic guinea pig(100728262) lectin, mannose-binding, 1
- sheep(101117293) lectin, mannose-binding, 1
- cow(511649) lectin, mannose-binding, 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LMAN1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ERGIC-53/p58 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
western blot
Anti-ERGIC-53 antibody, Mouse monoclonal, clone ERGIC-3, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
western blot