KISS1
KiSS-1 metastasis-suppressor
Synonyms:
HH13, KiSS-1
Species:
Human KISS1 (3814), Mouse Kiss1 (280287), Rat Kiss1 (289023), Horse KISS1 (100054297), sheep KISS1 (101107719), domestic cat KISS1 (101083480), sheep KISS1 (100294562), cow KISS1 (615613), Zebrafish kiss1 (100134982), domestic guinea pig Kiss1 (100720081)
UniProtKB ID:
Gene ID:
- Human(3814) Summary: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]
- Mouse(280287) KiSS-1 metastasis-suppressor
- Rat(289023) KiSS-1 metastasis-suppressor
- Horse(100054297) KiSS-1 metastasis-suppressor
- sheep(101107719) KiSS-1 metastasis-suppressor
- domestic cat(101083480) KiSS-1 metastasis-suppressor
- sheep(100294562) KiSS-1 metastasis-suppressor
- cow(615613) KiSS-1 metastasis-suppressor
- Zebrafish(100134982) KiSS-1 metastasis-suppressor
- domestic guinea pig(100720081) KiSS-1 metastasis-suppressor
- Goat(100860861) KiSS-1 metastasis-suppressor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-KISS1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-KISS1 antibody produced in mouse, clone 1F7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species