KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
Synonyms:
ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1
Species:
Human KCNA5 (3741), Mouse Kcna5 (16493), Rat Kcna5 (25470), cow KCNA5 (508960), domestic cat KCNA5 (101100573), dog KCNA5 (403995), chicken KCNA5 (395115), naked mole-rat Kcna5 (101715453), domestic guinea pig Kcna5 (100732253), Domestic Rabbit KCNA5 (100008684)
UniProtKB ID:
Gene ID:
- Human(3741) Summary: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012]
- Mouse(16493) potassium voltage-gated channel, shaker-related subfamily, member 5
- Rat(25470) potassium voltage-gated channel, shaker-related subfamily, member 5
- cow(508960) potassium voltage-gated channel, shaker-related subfamily, member 5
- domestic cat(101100573) potassium voltage-gated channel, shaker-related subfamily, member 5
- dog(403995) potassium voltage-gated channel, shaker-related subfamily, member 5
- chicken(395115) potassium voltage-gated channel, shaker-related subfamily, member 5
- naked mole-rat(101715453) potassium voltage-gated channel, shaker-related subfamily, member 5
- domestic guinea pig(100732253) potassium voltage-gated channel, shaker-related subfamily, member 5
- Domestic Rabbit(100008684) potassium voltage-gated channel, shaker-related subfamily, member 5
- sheep(101111448) potassium voltage-gated channel, shaker-related subfamily, member 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-KCNA5 antibody produced in mouse, clone S7-45, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Blocker
Product Number
Description
Species