IRF4
interferon regulatory factor 4
Synonyms:
LSIRF, MUM1, NF-EM5
Species:
Human IRF4 (3662), Mouse Irf4 (16364), Rat Irf4 (291100), naked mole-rat Irf4 (101705637), domestic guinea pig Irf4 (100719564), sheep IRF4 (101111234), cow IRF4 (506141), chicken IRF4 (374179), domestic cat IRF4 (101089438), Horse IRF4 (100049827)
UniProtKB ID:
Gene ID:
- Human(3662) Summary: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
- Mouse(16364) interferon regulatory factor 4
- Rat(291100) interferon regulatory factor 4
- naked mole-rat(101705637) interferon regulatory factor 4
- domestic guinea pig(100719564) interferon regulatory factor 4
- sheep(101111234) interferon regulatory factor 4
- cow(506141) interferon regulatory factor 4
- chicken(374179) interferon regulatory factor 4
- domestic cat(101089438) interferon regulatory factor 4
- Horse(100049827) interferon regulatory factor 4
- Horse(100068881) interferon regulatory factor 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IRF4 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-MUM1/IRF4 antibody, Rabbit monoclonal, clone SP114, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
bovine, chicken, dog, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-IRF4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
western blot