IRAK4
interleukin-1 receptor-associated kinase 4
Synonyms:
IPD1, IRAK-4, NY-REN-64, REN64
Species:
Human IRAK4 (51135), Mouse Irak4 (266632), Rat Irak4 (300177), Zebrafish irak4 (393132), chicken IRAK4 (417796), Horse IRAK4 (100054848), domestic cat IRAK4 (101100225), dog IRAK4 (486601), Domestic Rabbit IRAK4 (100341605), sheep IRAK4 (100216438) ...More
UniProtKB ID:
Gene ID:
- Human(51135) Summary: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- Mouse(266632) interleukin-1 receptor-associated kinase 4
- Rat(300177) interleukin-1 receptor-associated kinase 4
- Zebrafish(393132) interleukin-1 receptor-associated kinase 4
- chicken(417796) interleukin-1 receptor-associated kinase 4
- Horse(100054848) interleukin-1 receptor-associated kinase 4
- domestic cat(101100225) interleukin-1 receptor-associated kinase 4
- dog(486601) interleukin-1 receptor-associated kinase 4
- Domestic Rabbit(100341605) interleukin-1 receptor-associated kinase 4
- sheep(100216438) interleukin-1 receptor-associated kinase 4
- cow(533692) interleukin-1 receptor-associated kinase 4
- naked mole-rat(101698190) interleukin-1 receptor-associated kinase 4
- domestic guinea pig(100729751) interleukin-1 receptor-associated kinase 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IRAK4 antibody produced in mouse, clone 1C3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunofluorescence
Anti-IRAK4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-IRAK4 antibody produced in mouse, clone 1D4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-IRAK-4 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Proteins
Product Number
Description
Species
IRAK4, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human