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Merck

IL2RA

interleukin 2 receptor, alpha

Synonyms:
CD25, IDDM10, IL2R, TCGFR
Species:
Human IL2RA (3559), Mouse Il2ra (16184), Rat Il2ra (25704), dog IL2RA (403870), chicken IL2RA (395294), cow IL2RA (281861), Horse IL2RA (100070292), domestic cat IL2RA (493953), domestic guinea pig Il2ra (100715332), sheep IL2RA (443435)
UniProtKB ID:
P01589, Q5W007
Gene ID:
  • Human(3559) Summary: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
  • Mouse(16184) interleukin 2 receptor, alpha chain
  • Rat(25704) interleukin 2 receptor, alpha
  • dog(403870) interleukin 2 receptor, alpha
  • chicken(395294) interleukin 2 receptor, alpha
  • cow(281861) interleukin 2 receptor, alpha
  • Horse(100070292) interleukin 2 receptor, alpha
  • domestic cat(493953) interleukin 2 receptor, alpha
  • domestic guinea pig(100715332) interleukin 2 receptor, alpha
  • sheep(443435) interleukin 2 receptor, alpha
  • naked mole-rat(101696651) interleukin 2 receptor, alpha

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4700364
Monoclonal Anti-CD25-PE antibody produced in mouse, clone MEM-181, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
SAB4700365
Monoclonal Anti-CD25 antibody produced in mouse, clone MEM-140, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
SAB5500055
Anti-CD25 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP176, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
SAB1305503
MONOCLONAL ANTI-CD25 antibody produced in mouse, clone 7G7B6, crude ascites, buffered aqueous solution,
Species Reactivity
human
Application
western blot
WH0003559M4
Monoclonal Anti-IL2RA antibody produced in mouse, clone 1D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
I0779
Interleukin-2 Soluble Receptor α human, >97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human