IL1B
interleukin 1, beta
Synonyms:
IL-1, IL1-BETA, IL1F2
Species:
Human IL1B (3553), Mouse Il1b (16176), Rat Il1b (24494), naked mole-rat Il1b (101704309), domestic guinea pig Il1b (100135556), Domestic Rabbit IL1B (100008990), cow IL1B (281251), chicken IL1B (395196), Goat IL1B (100860816), Horse IL1B (100034237) ...More
UniProtKB ID:
Gene ID:
- Human(3553) Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
- Mouse(16176) interleukin 1 beta
- Rat(24494) interleukin 1 beta
- naked mole-rat(101704309) interleukin 1, beta
- domestic guinea pig(100135556) interleukin 1 beta
- Domestic Rabbit(100008990) interleukin 1, beta
- cow(281251) interleukin 1, beta
- chicken(395196) interleukin 1, beta
- Goat(100860816) interleukin 1, beta
- Horse(100034237) interleukin 1, beta
- dog(403974) interleukin 1, beta
- Zebrafish(557541) interleukin 1, beta
- Zebrafish(405770) interleukin 1, beta
- domestic cat(768274) interleukin 1, beta
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ELISA
Product Number
Description
Species
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IL1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Interleukin-1β antibody produced in goat, IgG fraction of antiserum,
Species Reactivity
mouse
Application
neutralization
western blot
western blot
Monoclonal Anti-IL1B antibody produced in mouse, clone 2A8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-IL1B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-IL1B antibody produced in mouse, clone 2E8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Interleukin-1β human, IL-1β, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture, endotoxin tested,
Species
human
IL-1 beta human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Interleukin-1β from mouse, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-1β from rat, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
rat