IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
Synonyms:
CLMF, IL-12A, NFSK, NKSF1, P35
Species:
Human IL12A (3592), Mouse Il12a (16159), Rat Il12a (84405), domestic guinea pig Il12a (100379543), chicken IL12A (407090), Zebrafish il12a (445410), Horse IL12A (100034215), domestic cat IL12A (493741), dog IL12A (403977), cow IL12A (281856) ...More
UniProtKB ID:
Gene ID:
- Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
- Mouse(16159) interleukin 12a
- Rat(84405) interleukin 12A
- domestic guinea pig(100379543) interleukin 12a
- chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- Zebrafish(445410) interleukin 12a
- Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
- naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
neutralization
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum,
Species Reactivity
mouse
Application
neutralization
western blot
western blot
Proteins
Product Number
Description
Species
IL-12 from mouse, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
IL-12 from rat, recombinant, expressed in baculovirus infected Sf9 cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Species
rat
IL-12 human, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
Interleukin-12 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-12 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
human