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Merck

IBSP

integrin-binding sialoprotein

Synonyms:
BNSP, BSP, BSP-II, SP-II
Species:
UniProtKB ID:
Gene ID:
  • Human(3381) Summary: The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
  • Mouse(15891) integrin binding sialoprotein
  • Rat(24477) integrin-binding sialoprotein
  • domestic guinea pig(100730180) integrin-binding sialoprotein
  • naked mole-rat(101725913) integrin-binding sialoprotein
  • chicken(396071) integrin-binding sialoprotein
  • dog(609146) integrin-binding sialoprotein
  • domestic cat(101095252) integrin-binding sialoprotein
  • cow(281233) integrin-binding sialoprotein
  • sheep(101120495) integrin-binding sialoprotein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IBSP antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot