HTRA2
HtrA serine peptidase 2
Synonyms:
OMI, PARK13, PRSS25
Species:
Human HTRA2 (27429), Mouse Htra2 (64704), Rat Htra2 (297376), domestic guinea pig Htra2 (100734064), dog HTRA2 (475782), cow HTRA2 (523039), fruit fly HtrA2 (41756), sheep HTRA2 (101120228), chicken HTRA2 (395990), naked mole-rat Htra2 (101725239) ...More
UniProtKB ID:
Gene ID:
- Human(27429) Summary: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq, Jul 2008]
- Mouse(64704) HtrA serine peptidase 2
- Rat(297376) HtrA serine peptidase 2
- domestic guinea pig(100734064) HtrA serine peptidase 2
- dog(475782) HtrA serine peptidase 2
- cow(523039) HtrA serine peptidase 2
- fruit fly(41756) CG8464 gene product from transcript CG8464-RB
- sheep(101120228) HtrA serine peptidase 2
- chicken(395990) HtrA serine peptidase 2
- naked mole-rat(101725239) HtrA serine peptidase 2
- Domestic Rabbit(100338967) HtrA serine peptidase 2
- domestic cat(768259) HtrA serine peptidase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HTRA2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-HtrA2 (C-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, rat
Application
western blot