HTR3A
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
Synonyms:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Species:
Human HTR3A (3359), Mouse Htr3a (15561), Rat Htr3a (79246), Domestic Rabbit HTR3A (100009570), chicken HTR3A (428247), domestic guinea pig Htr3a (100135547), Horse HTR3A (100009690), naked mole-rat Htr3a (101714088), sheep HTR3A (101110536), dog HTR3A (489399) ...More
UniProtKB ID:
Gene ID:
- Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
- Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
- Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
- cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
- domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
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Small Molecule - Agonist
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Description
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Small Molecule - Allosteric Modulator
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Small Molecule - Antagonist
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Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Ondansetron for LC system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Ondansetron for TLC system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Blocker
Small Molecule - Inhibitor
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Small Molecule - Ligand
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Small Molecule - Metabolite
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Small Molecule - Precursor
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