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Merck

HRH3

histamine receptor H3

Synonyms:
GPCR97, HH3R
Species:
UniProtKB ID:
Gene ID:
  • Human(11255) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
  • Mouse(99296) histamine receptor H3
  • Rat(85268) histamine receptor H3
  • sheep(101121700) histamine receptor H3
  • Domestic Rabbit(100009035) histamine receptor H3
  • chicken(428147) histamine receptor H3
  • dog(477282) histamine receptor H3
  • domestic cat(101084437) histamine receptor H3
  • cow(789851) histamine receptor H3
  • Zebrafish(561773) histamine receptor H3
  • domestic guinea pig(100135541) histamine receptor H3

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Small Molecule - Agonist

Product Number
Description
Species
Imetit dihydrobromide, ≥98% (HPLC),
Species
human
(R)(−)-α-Methylhistamine dihydrochloride, solid, ≥98% (HPLC),
Species
human
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
2-(2-Methylaminoethyl)pyridine, 97%,
Species
human
Betahistine dihydrochloride, ≥98%,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Thioperamide maleate salt, solid,
Species
human
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
2-(2-Methylaminoethyl)pyridine, 97%,
Species
human
Betahistine dihydrochloride, ≥98%,
Species
human
Betahistine dihydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-H3 Histamine Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
Histamine, ≥97.0%,
Species
human, rat

Small Molecule - Metabolite

Product Number
Description
Species
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Species
human