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Merck

HNRNPL

heterogeneous nuclear ribonucleoprotein L

Synonyms:
HNRPL, hnRNP-L
Species:
UniProtKB ID:
Gene ID:
  • Human(3191) Summary: Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(15388) heterogeneous nuclear ribonucleoprotein L
  • Rat(80846) heterogeneous nuclear ribonucleoprotein L
  • sheep(101113093) heterogeneous nuclear ribonucleoprotein L
  • naked mole-rat(101713537) heterogeneous nuclear ribonucleoprotein L
  • domestic guinea pig(100734238) heterogeneous nuclear ribonucleoprotein L
  • dog(476466) heterogeneous nuclear ribonucleoprotein L
  • cow(504520) heterogeneous nuclear ribonucleoprotein L
  • Horse(100066483) heterogeneous nuclear ribonucleoprotein L
  • domestic cat(101099920) heterogeneous nuclear ribonucleoprotein L

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HNRNP L antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-hnRNP-L antibody, Mouse monoclonal, clone 4D11, purified from hybridoma cell culture,
Species Reactivity
bovine, chicken, human, monkey, mouse, newt
Application
ELISA
immunocytochemistry

immunoprecipitation (IP)

microarray

western blot