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Merck

GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

Synonyms:
CAE2, ECA2, GEFSP3
Species:
UniProtKB ID:
Gene ID:
  • Human(2566) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14406) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  • Rat(29709) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Horse(100059571) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • sheep(101118526) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Zebrafish(553402) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • chicken(396289) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • dog(489141) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic cat(100286791) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • cow(282240) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic guinea pig(100723005) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • naked mole-rat(101718598) gamma-aminobutyric acid (GABA) A receptor, gamma 2

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Small Molecule - Agonist

Product Number
Description
Species
Oxazepam, ,
Species
human
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Meprobamate, analytical standard,
Species
human
γ-Aminobutyric acid, ≥99%,
Species
human, rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
5α-Pregnan-3α-ol-11,20-dione, powder, ≥98% (TLC),
Species
human
Zolpidem, ≥98% (HPLC), solid,
Species
human, rat
Oxazepam, ,
Species
human
Midazolam maleate salt, ,
Species
human
Triazolam, ,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Etiocholan-3α-ol-17-one, ,
Species
human, rat
Ethyl β-carboline-3-carboxylate, 97%,
Species
human
Zolpidem, ≥98% (HPLC), solid,
Species
human, rat
Triazolam, ,
Species
human
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
bovine, human, mouse, rat
Application
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Etiocholan-3α-ol-17-one, ,
Species
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
Diazepam solution, 1.0 mg/mL in methanol, analytical standard, for drug analysis,
Species
human, mouse, rat
5α-Pregnan-3α-ol-20-one, solid,
Species
human, mouse, rat