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FOXP2

forkhead box P2

Synonyms:
CAGH44, SPCH1, TNRC10
Species:
UniProtKB ID:
Gene ID:
  • Human(93986) Summary: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(114142) forkhead box P2
  • Rat(500037) forkhead box P2
  • domestic cat(100134847) forkhead box P2
  • dog(482413) forkhead box P2
  • Domestic Rabbit(100328793) forkhead box P2
  • naked mole-rat(101699542) forkhead box P2
  • chicken(769935) forkhead box P2
  • Zebrafish(555242) forkhead box P2
  • sheep(101110051) forkhead box P2
  • domestic guinea pig(100717297) forkhead box P2
  • Goat(100860795) forkhead box P2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FOXP2 (Internal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-FOXP2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5310, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-FOXP2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5312, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
Anti-FOXP2 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
microarray
western blot