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Merck

FBXO32

F-box protein 32

Synonyms:
Fbx32, MAFbx
Species:
Human FBXO32 (114907), Mouse Fbxo32 (67731), Rat Fbxo32 (171043), domestic cat FBXO32 (101083398), Horse FBXO32 (100057506), Zebrafish fbxo32 (393891), chicken FBXO32 (420343), domestic guinea pig Fbxo32 (100726187), naked mole-rat Fbxo32 (101718496), sheep FBXO32 (100142676) ...More
UniProtKB ID:
Q969P5, A4KYM0
Gene ID:
  • Human(114907) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
  • Mouse(67731) F-box protein 32
  • Rat(171043) F-box protein 32
  • domestic cat(101083398) F-box protein 32
  • Horse(100057506) F-box protein 32
  • Zebrafish(393891) F-box protein 32
  • chicken(420343) F-box protein 32
  • domestic guinea pig(100726187) F-box protein 32
  • naked mole-rat(101718496) F-box protein 32
  • sheep(100142676) F-box protein 32
  • cow(513776) F-box protein 32
  • Domestic Rabbit(100356177) F-box protein 32
  • dog(475091) F-box protein 32

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2501208
Anti-FBXO32 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB1408235
Anti-FBXO32 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot