F3
coagulation factor III (thromboplastin, tissue factor)
Synonyms:
CD142, TF, TFA
Species:
Human F3 (2152), Mouse F3 (14066), Rat F3 (25584), naked mole-rat F3 (101702267), domestic guinea pig F3 (100135463), Domestic Rabbit F3 (100009127), sheep F3 (101118918), cow F3 (280686), domestic cat F3 (101082330), dog F3 (490153)
UniProtKB ID:
Gene ID:
- Human(2152) Summary: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Mouse(14066) coagulation factor III
- Rat(25584) coagulation factor III (thromboplastin, tissue factor)
- naked mole-rat(101702267) coagulation factor III (thromboplastin, tissue factor)
- domestic guinea pig(100135463) coagulation factor III
- Domestic Rabbit(100009127) coagulation factor III (thromboplastin, tissue factor)
- sheep(101118918) coagulation factor III (thromboplastin, tissue factor)
- cow(280686) coagulation factor III
- domestic cat(101082330) coagulation factor III (thromboplastin, tissue factor)
- dog(490153) coagulation factor III (thromboplastin, tissue factor)
- chicken(429084) coagulation factor III (thromboplastin, tissue factor)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-F3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-F3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3807, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species