EPOR
erythropoietin receptor
Synonyms:
EPO-R
Species:
Human EPOR (2057), Mouse Epor (13857), Rat Epor (24336), dog EPOR (484943), domestic cat EPOR (101081364), naked mole-rat Epor (101710668), cow EPOR (281144), domestic guinea pig Epor (100721190), Zebrafish epor (751109), sheep EPOR (443227)
UniProtKB ID:
Gene ID:
- Human(2057) Summary: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Mouse(13857) erythropoietin receptor
- Rat(24336) erythropoietin receptor
- dog(484943) erythropoietin receptor
- domestic cat(101081364) erythropoietin receptor
- naked mole-rat(101710668) erythropoietin receptor
- cow(281144) erythropoietin receptor
- domestic guinea pig(100721190) erythropoietin receptor
- Zebrafish(751109) erythropoietin receptor
- sheep(443227) erythropoietin receptor
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-EPOR antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Erythropoietin Receptor antibody produced in goat, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-EPO-R antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-EPOR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human, mouse, rat
Application
western blot