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Merck

DYNLL1

dynein, light chain, LC8-type 1

Synonyms:
DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, PIN, hdlc1
Species:
Human DYNLL1 (8655), Mouse Dynll1 (56455), Rat Dynll1 (58945), cow DYNLL1 (404151), Zebrafish dynll1 (406297), naked mole-rat Dynll1 (101696473), chicken DYNLL1 (100859081), domestic cat DYNLL1 (101096515), domestic guinea pig Dynll1 (100721653), sheep DYNLL1 (101118902)
UniProtKB ID:
P63167, Q15701
Gene ID:
  • Human(8655) Summary: Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(56455) dynein light chain LC8-type 1
  • Rat(58945) dynein light chain LC8-type 1
  • cow(404151) dynein, light chain, LC8-type 1
  • Zebrafish(406297) dynein, light chain, LC8-type 1
  • naked mole-rat(101696473) dynein, light chain, LC8-type 1
  • chicken(100859081) dynein light chain 1, cytoplasmic-like
  • domestic cat(101096515) dynein, light chain, LC8-type 1
  • domestic guinea pig(100721653) dynein, light chain, LC8-type 1
  • sheep(101118902) dynein, light chain, LC8-type 1
  • Domestic Rabbit(100008650) dynein, light chain, LC8-type 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1402996
Monoclonal Anti-DYNLL1, (N-terminal) antibody produced in mouse, clone 1H7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot