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Merck

DPYSL2

dihydropyrimidinase-like 2

Synonyms:
CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2
Species:
UniProtKB ID:
Gene ID:
  • Human(1808) Summary: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(12934) dihydropyrimidinase-like 2
  • Rat(25416) dihydropyrimidinase-like 2
  • naked mole-rat(101710925) dihydropyrimidinase-like 2
  • dog(486107) dihydropyrimidinase-like 2
  • chicken(395155) dihydropyrimidinase-like 2
  • sheep(101108984) dihydropyrimidinase-like 2
  • Domestic Rabbit(100351135) dihydropyrimidinase-like 2
  • cow(533746) dihydropyrimidinase-like 2
  • domestic cat(554340) dihydropyrimidinase-like 2
  • domestic guinea pig(100734407) dihydropyrimidinase-like 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DRP-2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CRMP-2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-CRMP-2 (pThr509) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-CRMP2 antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot