DOCK2
dedicator of cytokinesis 2
Synonyms:
Species:
Human DOCK2 (1794), Mouse Dock2 (94176), Rat Dock2 (360509), Zebrafish dock2 (100330200), Zebrafish dock2 (571408), domestic cat DOCK2 (101097544), sheep DOCK2 (101104011), domestic guinea pig Dock2 (100714041), cow DOCK2 (281745), naked mole-rat Dock2 (101707633) ...More
UniProtKB ID:
Gene ID:
- Human(1794) Summary: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection. [provided by RefSeq, Oct 2011]
- Mouse(94176) dedicator of cyto-kinesis 2
- Rat(360509) dedicator of cytokinesis 2
- Zebrafish(100330200) dedicator of cytokinesis 2
- Zebrafish(571408) dedicator of cyto-kinesis 2
- domestic cat(101097544) dedicator of cytokinesis 2
- sheep(101104011) dedicator of cytokinesis 2
- domestic guinea pig(100714041) dedicator of cytokinesis 2
- cow(281745) dedicator of cytokinesis 2
- naked mole-rat(101707633) dedicator of cytokinesis 2
- dog(489128) dedicator of cytokinesis 2
- cow(510083) dedicator of cytokinesis 2
- Horse(100070446) dedicator of cytokinesis 2
- chicken(427612) dedicator of cytokinesis 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DOCK2 antibody produced in rabbit, whole antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-DOCK2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot