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Merck

DHX8

DEAH (Asp-Glu-Ala-His) box polypeptide 8

Synonyms:
DDX8, HRH1, PRP22, PRPF22
Species:
Human DHX8 (1659), Mouse Dhx8 (217207), Rat Dhx8 (287727), chicken DHX8 (419982), Zebrafish dhx8 (606595), Horse DHX8 (100051804), domestic cat DHX8 (101094639), dog DHX8 (480507), sheep DHX8 (101110072), cow DHX8 (536093) ...More
UniProtKB ID:
Q14562
Gene ID:
  • Human(1659) Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [provided by RefSeq, Jul 2008]
  • Mouse(217207) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • Rat(287727) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • chicken(419982) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • Zebrafish(606595) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • Horse(100051804) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • domestic cat(101094639) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • dog(480507) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • sheep(101110072) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • cow(536093) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • naked mole-rat(101704043) DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • domestic guinea pig(100722807) DEAH (Asp-Glu-Ala-His) box polypeptide 8

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