CTSE
cathepsin E
Synonyms:
CATE
Species:
Human CTSE (1510), Mouse Ctse (13034), Rat Ctse (25424), domestic guinea pig Ctse (100135509), naked mole-rat Ctse (101699894), dog CTSE (488577), Horse CTSE (100055161), cow CTSE (281106), Domestic Rabbit CTSE (100009063), chicken CTSE (771791)
UniProtKB ID:
Gene ID:
- Human(1510) Summary: The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13034) cathepsin E
- Rat(25424) cathepsin E
- domestic guinea pig(100135509) cathepsin E
- naked mole-rat(101699894) cathepsin E
- dog(488577) cathepsin E
- Horse(100055161) cathepsin E
- cow(281106) cathepsin E
- Domestic Rabbit(100009063) cathepsin E
- chicken(771791) cathepsin E
- domestic cat(101088455) cathepsin E
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Small Molecule - Substrate
Product Number
Description
Species
7-Methoxycoumarin-4-Acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(DNP)-D-Arg-amide, >97% (HPLC), solid,
Species
mouse, human, rat