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Merck

CRADD

CASP2 and RIPK1 domain containing adaptor with death domain

Synonyms:
MRT34, RAIDD
Species:
Human CRADD (8738), Mouse Cradd (12905), Rat Cradd (314756), sheep CRADD (101115270), cow CRADD (615788), chicken CRADD (417900), domestic guinea pig Cradd (100714422), domestic cat CRADD (101081233), naked mole-rat Cradd (101716016), dog CRADD (482604)
UniProtKB ID:
P78560
Gene ID:
  • Human(8738) Summary: The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008]
  • Mouse(12905) CASP2 and RIPK1 domain containing adaptor with death domain
  • Rat(314756) CASP2 and RIPK1 domain containing adaptor with death domain
  • sheep(101115270) CASP2 and RIPK1 domain containing adaptor with death domain
  • cow(615788) CASP2 and RIPK1 domain containing adaptor with death domain
  • chicken(417900) CASP2 and RIPK1 domain containing adaptor with death domain
  • domestic guinea pig(100714422) CASP2 and RIPK1 domain containing adaptor with death domain
  • domestic cat(101081233) CASP2 and RIPK1 domain containing adaptor with death domain
  • naked mole-rat(101716016) CASP2 and RIPK1 domain containing adaptor with death domain
  • dog(482604) CASP2 and RIPK1 domain containing adaptor with death domain
  • Zebrafish(450046) CASP2 and RIPK1 domain containing adaptor with death domain

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