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Merck

COX6B1

cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)

Synonyms:
COX6B, COXG, COXVIb1
Species:
Human COX6B1 (1340), Mouse Cox6b1 (110323), Rat Cox6b1 (502592), cow COX6B1 (100270792), Zebrafish cox6b1 (436968)
UniProtKB ID:
P14854, B2R5C9, Q6IBL4
Gene ID:
  • Human(1340) Summary: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq, Jan 2010]
  • Mouse(110323) cytochrome c oxidase, subunit VIb polypeptide 1
  • Rat(502592) cytochrome c oxidase, subunit VIb polypeptide 1
  • cow(100270792) cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
  • Zebrafish(436968) cytochrome c oxidase subunit VIb polypeptide 1

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