CHMP2B
charged multivesicular body protein 2B
Synonyms:
ALS17, CHMP2.5, DMT1, VPS2-2, VPS2B
Species:
Human CHMP2B (25978), Mouse Chmp2b (68942), Rat Chmp2b (363720), fruit fly CHMP2B (38599), domestic guinea pig Chmp2b (100734811), naked mole-rat Chmp2b (101717020), sheep CHMP2B (101121224), dog CHMP2B (487675), chicken CHMP2B (418461), cow CHMP2B (615954)
UniProtKB ID:
Gene ID:
- Human(25978) Summary: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
- Mouse(68942) charged multivesicular body protein 2B
- Rat(363720) charged multivesicular body protein 2B
- fruit fly(38599) Charged multivesicular body protein 2b
- domestic guinea pig(100734811) charged multivesicular body protein 2B
- naked mole-rat(101717020) charged multivesicular body protein 2B
- sheep(101121224) charged multivesicular body protein 2B
- dog(487675) charged multivesicular body protein 2B
- chicken(418461) charged multivesicular body protein 2B
- cow(615954) charged multivesicular body protein 2B
- domestic cat(101099491) charged multivesicular body protein 2B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.