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Merck

CFL2

cofilin 2 (muscle)

Synonyms:
NEM7
Species:
UniProtKB ID:
Gene ID:
  • Human(1073) Summary: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
  • Mouse(12632) cofilin 2, muscle
  • Rat(366624) cofilin 2, muscle
  • Zebrafish(403001) cofilin 2 (muscle)
  • domestic cat(101083089) cofilin 2 (muscle)
  • cow(539332) cofilin 2 (muscle)
  • domestic guinea pig(100727405) cofilin 2 (muscle)
  • dog(490649) cofilin 2 (muscle)
  • sheep(101118388) cofilin 2 (muscle)
  • chicken(423320) cofilin 2 (muscle)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Cofilin antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-Cofilin 2 (muscle) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, pig, rat, sheep
Application
ELISA
immunohistochemistry

western blot
Anti-CCFL1/CFL2 (Ab-88) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Cofilin antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
immunofluorescence
microarray

western blot