CEP170
centrosomal protein 170kDa
Synonyms:
FAM68A, KAB, KIAA0470
Species:
Human CEP170 (9859), Mouse Cep170 (545389), Rat Cep170 (171457), Domestic Rabbit CEP170 (100342565), domestic guinea pig Cep170 (100718787), dog CEP170 (480096), chicken CEP170 (421499), cow CEP170 (529230), Horse CEP170 (100054866), sheep CEP170 (101119149) ...More
UniProtKB ID:
Gene ID:
- Human(9859) Summary: The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(545389) centrosomal protein 170
- Rat(171457) centrosomal protein 170
- Domestic Rabbit(100342565) centrosomal protein 170kDa
- domestic guinea pig(100718787) centrosomal protein 170kDa
- dog(480096) centrosomal protein 170kDa
- chicken(421499) centrosomal protein 170kDa
- cow(529230) centrosomal protein 170kDa
- Horse(100054866) centrosomal protein 170kDa
- sheep(101119149) centrosomal protein 170kDa
- domestic cat(101089733) centrosomal protein 170kDa
- naked mole-rat(101703041) centrosomal protein 170kDa
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